[Treatment of ulcerative colitis with azathioprine].
نویسنده
چکیده
Azathioprine (Imuran) was administered to seven patients with ulcerative colitis suffering from a relapse which could not be controlled by adrenocortical steroids. In four patients remission started one to two weeks after initiation of antimetabolite therapy. Corticosteroid administration was continued concurrently with azathioprine, but the dosage could be reduced and in one case they were withdrawn.Apart from transient leucopenia in two cases, and transient nausea and vomiting in two, no complications were encountered.
منابع مشابه
Evaluation of low doses of Azathioprine in reducing relapse and corticosteroid dependence in patients with Ulcerative Colitis
Background and Aim: Ulcerative Colitis is an idiopathic inflammatory bowel disease that is common in adults. Although corticosteroids are the most effective preservative treatment for Ulcerative Colitis. However, due to the dependence of these drugs and their serious complications, the use of an immunosuppressive drug or surgery should be taken seriously. Thus the aim of the study was the evalu...
متن کاملTraditional Chinese medicine combination therapy for patients with steroid-dependent ulcerative colitis: study protocol for a randomized controlled trial
BACKGROUND Approximately 20% of patients with ulcerative colitis become steroid dependent. Azathioprine is recommended in steroid-dependent ulcerative colitis, but its side effects limit its use. Chinese herbal medicine has been widely used to treat ulcerative colitis in China. However, its effectiveness in steroid-dependent patients has not been evaluated. This study aims to investigate the ef...
متن کاملInfliximab treatment in a paediatric patient with ulcerative colitis, who developed acute pancreatitis due to azathioprine during follow-up
متن کامل
Azathioprine in ulcerative colitis: final report on controlled therapeutic trial.
Eighty patients, all of whom were suffering from a frank clinical attack of ulcerative colitis, were admitted to the trial. The attack was treated with a standard course of corticosteroids and the patients were immediately placed on treatment with either azathioprine in a dose of 2.5 mg/kg body weight or dummy tablets. The trial tablets were continued for one year while the patients were mainta...
متن کاملListeria meningitis in an immunocompromised patient with ulcerative colitis: Report of a case and review of the literature
This is the case of a patient with total ulcerative colitis on long-term treatment with corticosteroids and azathioprine and development of Listeria meningitis. Diagnosis was confirmed with cerebrospinal fluid culture. The patient responded favorably to specific treatment with a combination of antibiotics. It was not clear whether infection originated from ingestion of contaminated food or from...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Das Deutsche Gesundheitswesen
دوره 26 22 شماره
صفحات -
تاریخ انتشار 1968